PREDIABETES

Pathology

Prediabetes, the preliminary stage of type 2 diabetes.
The term prediabetes is used to describe impaired glucose tolerance and/or abnormal fasting blood glucose levels. According to the World Health Organization, prediabetes is defined as fasting hyperglycaemia (when the blood sugar is between 1.10 g/l and 1.25 g/l) after an eight-hour fast and checked twice, and/or impaired glucose tolerance (blood glucose on venous plasma between 1.4 g/l and 1.99 g/l) two hours after an oral glycaemic load of 75 g. The American Diabetes Association (ADA) has even reduced the threshold for defining impaired fasting glucose to 1.10 g/l, which has significantly increased the number prediabetes diagnoses. The management of prediabetes starts with diet, dietary behaviour and physical exercise, but these recommendations are not always followed or enough.

PREDIABETES

Pathology

Prediabetes, the preliminary stage of type 2 diabetes.
The term prediabetes is used to describe impaired glucose tolerance and/or abnormal fasting blood glucose levels. According to the World Health Organization, prediabetes is defined as fasting hyperglycaemia (when the blood sugar is between 1.10 g/l and 1.25 g/l) after an eight-hour fast and checked twice, and/or impaired glucose tolerance (blood glucose on venous plasma between 1.4 g/l and 1.99 g/l) two hours after an oral glycaemic load of 75 g. The American Diabetes Association (ADA) has even reduced the threshold for defining impaired fasting glucose to 1.10 g/l, which has significantly increased the number prediabetes diagnoses. The management of prediabetes starts with diet, dietary behaviour and physical exercise, but these recommendations are not always followed or enough.

Issue

Diabetes is a global health issue. As a matter of fact, diabetes is responsible for serious complications such as blindness, kidney failure, heart and cerebral vascular accidents, and lower limb amputations etc – all over the world, including in low-income countries where it is becoming more prevalent more rapidly. It is therefore necessary to manage people with high but normal blood sugar levels before they exceed the thresholds and thus prevent them from progressing to the diseased stage of type 2 diabetes.

Issue

Diabetes is a global health issue. As a matter of fact, diabetes is responsible for serious complications such as blindness, kidney failure, heart and cerebral vascular accidents, and lower limb amputations etc – all over the world, including in low-income countries where it is becoming more prevalent more rapidly. It is therefore necessary to manage people with high but normal blood sugar levels before they exceed the thresholds and thus prevent them from progressing to the diseased stage of type 2 diabetes.

Key figures

The International Diabetes Federation estimates that there are over 460 million people with diabetes worldwide, and this figure could rise to 700 million by 2045.

An estimated 373 million people worldwide have impaired glucose tolerance today, and this number could reach 454 million by 2030 and 548 million by 2045.

Diabetes killed over 4.2 million people in 2019 and is thought to be responsible for at least $760 billion in healthcare expenditure, more than 10% of global healthcare spending.

Source : Fédération internationale du diabète